ISSN 1662-4009 (online)

ey0017.3-13 | Clinical trials for thyroid disease | ESPEYB17

3.13. Cognitive function in children with idiopathic subclinical hypothyroidism: Effects of 2 years of levothyroxine therapy

D Capalbo , S Alfano , M Polizzi , R Di Mase , N Improda , A Esposito , C Bravaccio , M Salerno

To read the full abstract: J Clin Endocrinol Metab. 2020;105:e774–e7781.This prospective non-randomized clinical trial investigated the effect of two-years levothyroxine treatment in children with subclinical hypothyroidism (TSH 5.0–9.9 mU/l with normal FT4 for two years preceding the study) starting at a mean age of 9 years. Capalbo et al. observed no change in IQ scores in 20 children after two-years of levothyroxine. Furthe...